Weber qualified for her first U.S. Women's Open by shooting 9-under-par 135 at Marin Country Club in Novata, Calif. The native of The Netherlands joined the Epson Tour in 2019 after playing collegiately at the University of Miami (Fla.). Over three seasons on the circuit, she posted 12 top-10 finishes, with a career-best fourth at the Mission Inn and Resort Club Championship in 2020. As an amateur, Weber lost in the title match of the 2016 British Ladies Amateur to Julia Engstrom, of Sweden, in 19 holes. She also was the runner-up to Duke's Virginia Elena Carta in the 2016 NCAA Championship at Eugene (Ore.) Country Club. She represented The Netherlands in the 2014 and 2016 Women's World Amateur Team Championships, and the International side in the 2018 Palmer Cup.